Detalhe da pesquisa
1.
Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.
N Engl J Med
; 386(23): 2178-2187, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35569036
2.
Circulating metabolic profile in idiopathic pulmonary fibrosis: data from the IPF-PRO Registry.
Respir Res
; 25(1): 58, 2024 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273290
3.
Integrative multi-omics analysis reveals novel idiopathic pulmonary fibrosis endotypes associated with disease progression.
Respir Res
; 24(1): 141, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344825
4.
Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.
Lung
; 200(1): 11-18, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35066606
5.
Circulating matrix metalloproteinases and tissue metalloproteinase inhibitors in patients with idiopathic pulmonary fibrosis in the multicenter IPF-PRO Registry cohort.
BMC Pulm Med
; 20(1): 64, 2020 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171287
6.
Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry.
Respir Res
; 20(1): 227, 2019 Oct 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31640794
7.
Correction to: Association of Circulating Proteins with Death or Lung Transplant in Patients with Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry Cohort.
Lung
; 200(1): 19, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35166906
8.
Corrigendum: BI 1015550 is a PDE4B inhibitor and a clinical drug candidate for the oral treatment of idiopathic pulmonary fibrosis.
Front Pharmacol
; 14: 1219760, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37324497
9.
BI 1015550 is a PDE4B Inhibitor and a Clinical Drug Candidate for the Oral Treatment of Idiopathic Pulmonary Fibrosis.
Front Pharmacol
; 13: 838449, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35517783
10.
Plain language summary: Clinical study of BI 1015550 as a potential treatment for idiopathic pulmonary fibrosis.
J Comp Eff Res
; 2022 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36537726
11.
Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.
Bioorg Med Chem Lett
; 21(14): 4228-32, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21684157
12.
Inhibition of inducible nitric oxide synthase in respiratory diseases.
Biochem Soc Trans
; 37(Pt 4): 886-91, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19614613
13.
BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.
Mol Pharmacol
; 73(4): 1244-53, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18178668
14.
Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
Circulation
; 108(10): 1238-45, 2003 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-12925450
15.
The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
Mol Pharmacol
; 69(1): 328-37, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16223957
16.
In vivo characterization of the novel imidazopyridine BYK191023 [2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine], a potent and highly selective inhibitor of inducible nitric-oxide synthase.
J Pharmacol Exp Ther
; 317(1): 181-7, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16368897
17.
Tetrahydrobiopterin, a critical factor in the production and role of nitric oxide in mast cells.
J Biol Chem
; 278(50): 50607-14, 2003 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-14514683
18.
Tetrahydrobiopterin precursor sepiapterin provides protection against neurotoxicity of 1-methyl-4-phenylpyridinium in nigral slice cultures.
J Neurochem
; 85(1): 214-23, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12641743
19.
Evidence for histamine as a transmitter in rat carotid body sensor cells.
J Neurochem
; 91(2): 493-500, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15447682